Neurology

Partial Volume and Relaxation Correction

Correction for Tissue Heterogeneity (Gm,Wm,CSF) in Large Spectroscopic Voxels

FSL-based tissue segmentation using high-res MRI. Convolution of tissue masks with PEPSI PSF:

PEPSI

Concentration of MR visible water:

PEPSI

Relaxation attenuation — literature T1/T2 values: (T1-values at 4T confirmed using long TR scan):

PEPSI

Relaxation and partial volume correction:

PEPSI

Where:

PEPSI