Publications of the Human MR Imaging Research Laboratory

Selected peer-reviewed: [most recent], Search PubMed

[1] Kiselev, V.G., Posse, S., “Theory of Susceptibility induced NMR Signal Dephasing in a Cerebrovascular Network ”, Physical Review Letters, 81:5696-5699, 1998.

[2] Dager, S., Layton, M.E., Strauss, W., Richards, T.L., Heide, A., Artru, A., Posse, S., “Human Brain Metabolic Response to Caffeine and the Effects of Tolerance ”, American Journal of Psychiatry, 156(2):229-237, 1999.

[3] Weckesser, M., Posse, S., Olthoff, U., Kemna, L., Dager, S., Müller Gärtner, H.-W., “Functional Imaging of the visual Cortex with BOLD-Contrast fMRI: Hyperventilation decreases the signal response ”, Magnetic Resonance in Medicine, 41(1): 213-216, 1999.

[4] Kiselev, V., Posse, S., “Analytical Model of Susceptibility induced MR Signal Dephasing: Effect of Diffusion in a Microvascular Network ”, Magnetic Resonance in Medicine, 41 (3): 499-509, 1999.

[5] Posse, S., Wiese, S., Gembris, D., Mathiak, K., Kessler, C., Grosse-Ruyken, M.-L., Elghawaghi, B., Richards, T., Dager, S. R., Kiselev, V.G., “Enhancement of BOLD-Contrast Sensitivity by Single-Shot Multi-Echo Functional MR Imaging ”, Magnetic Resonance in Medicine, 42 (1): 87-97, 1999.

[6] Gembris, D., Taylor, J.G., Schor, S., Frings, W., Suter, D., Posse, S., “Functional MR Imaging in Real-Time using a sliding-window correlation technique ”, Magnetic Resonance in Medicine, 43: 259-268, 2000.

[7] Schneider, F., Weiss, U., Salloum, J.B., Kesler, C., Posse, S., “Gender Differences in Regional Cerebral Blood Flow during Sadness ”, Human Brain Mapping, 9, 226-238, 2000.

[8] Mathiak, K., Posse, S., “Evaluation of Motion and Realignment for Functional Magnetic Resonance Imaging in Realtime ”, Magnetic Resonance in Medicine, 45(1):167-171, 2001.


[9] Posse, S., Binkofski, F., Schneider, F., Gembris, D., Wiese, S., Kiselev, V., Graf, T., Elghawaghi, B., Eickermann, T., “A New Approach to Measure Single Event Related Brain Activity using Real-Time fMRI: Feasibility of sensory, motor, and higher cognitive tasks ”, Human Brain Mapping, 12(1); 25-41, 2001.

[10] Posse, S., Kemna, L.J., Wiese, S., Elghahwagi, B., Kiselev, V.G., “Dependence of fMRI Contrast on graded Hypo- and Hypercapnia using Whole Brain T2*-Mapping”, Magnetic Resonance in Medicine, 46, 264-271, 2001.

[11] Kemna, L.J., Posse, S., “Effect of Respiratory CO2 Changes on the Shape of the Hemodynamic Response in Functional MR Imaging ”, NeuroImage, 14 (3), 642-649, 2001.

[12] Kemna, L.J., Posse, S., Tellmann, L., Schmitz, T., Herzog, H., “ Interdependence of Regional and Global Cerebral Blood Flow During Visual Stimulation: An O-15 Butanol Positron Emission Tomography Study ”, J. Cerebr. Blood Flow Metab., 21, 664-670, 2001.

[13] Posse, S., Shen, Z., Kiselev, V.G., Kemna, L.J., “Single-Shot T2* Mapping with 3D Compensation of Local Susceptibility Gradients in Multiple Regions ”, NeuroImage 2003 February, 18(2):390-400.

[14] Posse, S., Fitzgerald, D., Gao, K., Habel, U., Rosenberg, D., Moore, G.J., Schneider, F.,“Real-time Functional Magnetic Resonance Imaging of Single Trial Amygdala Activation during Self-Induced Sadness ”, NeuroImage, 18, 760-768, 2003.

[15] Chu, A., Alger, J.R., Moore, G.J., Posse,S.,“Proton-Echo-Planar-Spectroscopic- Imaging with Highly Effective Outer Volume Suppression using Combined Presaturation and Spatially Selective Echo Dephasing: COMPRESSED-PEPSI ”, Magnetic Resonance in Medicine, 49:817-821, 2003.

[16] Nitschke, M.F., Binkofski, F., Buccino, G., Posse, S., Erdmann, C., Kömpf, D., Seitz, R.J., Heide, W.,“Activation of cerebellar hemispheres in spatial memorization of saccadic eye movements - an fMRI study ”, Human Brain Mapping, 2004 June, 22(2):155-64.


[17] Fitzgerald DA, Posse S, Moore GJ, Tancer ME, Nathan PJ, Phan KL., “Neural correlates of internally-generated disgust via autobiographical recall: A functional magnetic resonance imaging investigation ”. Neurosci Lett. 2004 Nov 11;370(2-3):91-6.

[18] Martínez-Ramón M., Koltchinsky V., Verzi, S., Heileman, G., Posse, S.,“fMRI pattern classification using neuroanatomically constrained boosting ”, Neuroimage, 2006 Jul 1;31(3):1129-41.

[19] Gasparovic, C., Song, T., Devier, D., Bockholt, J., Caprihan, A., Mullins, P., Posse, S., Jung, R., Morrison, L.,“The Use of Tissue Water as a Concentration Reference for Proton Spectroscopic Imaging ”. Magn. Reson. Med., 2006 Jun;55(6):1219-26.

[20] Mayer, A.R., Xu, J., Para-Blagoev, J., Posse, S.,“Reproducibility of Activation in Broca’s Area During Covert Generation of Single Words at High Field: A Single Trial FMRI Study at 4 Tesla ”, Neuroimage, 2006 Aug 1;32(1):129-37.

[21] Otazo, R., Mueller, B., Ugurbil, K., Wald, L.L., Posse, S., “Signal-to-Noise Ratio and Spectral Line Width Improvements between 1.5 and 7 Tesla in Proton-Echo-Planar-Spectroscopic-Imaging (PEPSI) ”. Magn Reson Med. 2006;56(6):1200-1210.

[22] Lin, F.-H., Tsai, S.-Y., Otazo, R., Caprihan, A., Wald, L.L., Belliveau, J.W., Posse, S., “Sensitivity-encoded (SENSE) Proton-Echo-Planar- Spectroscopic-Imaging (PEPSI) in Human Brain ”, Magn. Reson. Med., Mag. Reson. Med. (2007), Vol. 57 (2), 249-257.

[23] Tsai, S-Y., Posse., S., Lin, Y.-R., Ko C.-W., Otazo, R., Chung, H.-W., Lin F.-H., “Fast Mapping of T2 Relaxation Time of Cerebral Metabolites using Proton-Echo-Planar-Spectroscopic-Imaging (PEPSI) ”, Magn. Reson. Med. (2007), Vol. 57 (5), 859-865.

[24] Posse, S., Otazo, R., Caprihan, A., Bustillo, J., Chen, H., Henry, P.-G., Marjanska, M., Gasparovic, C., Zuo, C., Magnotta, V., Mueller, B., Mullins, P., Renshaw, P., Ugurbil, K., Lim, K.O., Alger,J..R., “Proton Echo Planar Spectroscopic Imaging of J-Coupled Resonances in Human Brain at 3 and 4 Tesla ”, Magn. Reson. Med. (2007), Vol 58, (2), 236 - 244.


[25] Otazo, R., Tsai, S-Y, Lin F-H, Posse, S.,“Highly Parallel Volumetric Echo-Planar Spectroscopic Imaging with 2D Acceleration ”, Magn. Reson. Med. (2007), 58(6):1107-16.

[26] Dager SR, Oskin NM, Richards TL, Posse S., “Research Applications of Magnetic Resonance Spectroscopy (MRS) to Investigate Psychiatric Disorders ”, Topics in MRI 2008;19:81-96.

[27] Tsai, S-Y, Posse, S.,Otazo, R., Lin Y-R, Chung, H-W, Lin F-H, “Accelerated Proton-Echo-Planar-Spectroscopy-Imaging (PEPSI) using GRAPPA with a 32-channel phased-array coil ”, Magn. Reson. Med. 2008 May;59(5):989-98.

[28] Posse, S., Otazo, R., Tsai S-Y, Lin F-H.,“Single-Shot MR Spectroscopic Imaging with Partial Parallel Imaging, Magnetic Resonance in Medicine ”, 2009 March; 61 (3), 541-547.

[29] Otazo, R., Lin, F.-H., Wiggins, G., Jordan, R., Sodickson, D., Posse, S.,“Superresolution Parallel Magnetic Resonance Imaging ”, Neuroimage, Volume 47, Issue 1, 1 August 2009, pp.220-230.

[30] Martínez-Ramón, M., Gallardo-Antolin, A., Heileman, G., Yung, KT, Zheng, W, Zhao C., Posse, S.,“Automatic Outer Volume Suppression (OVS) Slice Placement for Proton-Echo-Planar-Spectroscopic-Imaging (PEPSI) ”, Magnetic Resonance in Medicine, Vol. 63, No 3, Feb. 2010, pp.592-600.

[31] Bustillo, J.R., Chen, H., Gasparovic, C., Mullins, P., Caprihan, A., Qualls, C., Apfeldorf, W., Lauriello, J., Posse, S.,“Glutamate as a cognitive marker in Schizophrenia: A proton spectroscopic imaging study at 4 Tesla ”, Biological Psychiatry, 2011 Jan 1;69(1):19-27. Epub 2010 Oct 20.

[32] Yung, KT, Zheng, W., Zhao, C., Martínez-Ramón, M., van der Kouwe, A., Posse, S.,“Atlas-Based Automated Positioning of Outer Volume Suppression Slices in Short-TE 3D MR Spectroscopic Imaging of the Human Brain ”, Magnetic Resonance in Medicine,2011 Oct;66(4)911-22.doi:10.1002/mrm.22887.Epub 2011 Apr 5.


[33] Posse, S., Ackley, E., Mutihac, R., Rick, J., Shane, M., Murray-Krezan, C., Zaitsev, M., Speck, O., “Enhancement of temporal resolution and BOLD sensitivity in real-time fMRI using multi-slab echo-volumar imaging ”, Neuroimage, 2012 Feb 28. doi:10.1016/j.neuroimage.2012.02.059.

[34] Zhao, C., Bolan, P.J., Royce, M., Lakkadi, N., Eberhardt, S., Sillerud, L., Lee, S.J., Posse, S., “Quantitative mapping of total choline in healthy human breast using proton echo planar spectroscopic imaging (PEPSI) at 3 Tesla ”, Journal of Magnetic Resonance Imaging, 2012 Jul 10.

[35] Zheng, W., Ackley, E.S., Martínez-Ramón, M., Posse, S., “Spatially aggregated multiclass pattern classification in functional MRI using optimally selected functional brain areas ”, Magnetic Resonance Imaging, 2012 Aug 16.

[36] Posse S., “ Multi-echo acquisition ”, Neuroimage, 2012 Aug 15;62(2):665-71.

[37] Posse, S., Otazo, R., Dager, S.R., Alger, J., “Magnetic Resonance Spectroscopic Imaging: Principles and Recent Advances ”, Journal of Magnetic Resonance Imaging, 2013 Jun; 37(6):1301-25., PMID: 23188775.

[38] Posse, S., Ackley, E., Mutihac, R., Zhang, T., Hummatov, R., Akhtari, M., Chohan M.O., Fisch, B., Yonas, H., “High-Speed Real-Time Resting State fMRI using Multi-Slab Echo-Volumar Imaging ”, Frontiers in Human Neuroscience,(7), 2013 Aug 26; doi:10.3389/fnhum.2013.00479.